Can Prebiotic Supplements Be Taken During Pregnancy Or While Breastfeeding?

June 23, 2025 · Oliver Drazsky

Key Takeaways

 

  • Prebiotics are safe and beneficial during pregnancy and breastfeeding.

  • They support gut health, immunity, and may aid fetal development.

  • Human milk oligosaccharides (HMOs) and Effera™ human lactoferrin offer unique, advanced benefits.

  • Consult your healthcare provider before starting any supplement.


Pregnancy and breastfeeding are times when women pay extra attention to their health and nutrition. Many wonder, are prebiotics safe during pregnancy? Others ask about taking a probiotic while nursing or want to know the benefits of prebiotics and pregnancy for their own well-being and their baby’s health. This article will answer these questions with clear, research-backed information, and help you decide if prebiotics pregnancy supplements are right for you. For more on prebiotic science and products, visit trykepos.com.


What Are Prebiotics and Why Do They Matter in Pregnancy?

 

Prebiotics are non-digestible fibers that serve as food for beneficial gut bacteria. Unlike probiotics, which are live bacteria, prebiotics help the good bacteria already present in your gut to grow and thrive. During pregnancy, the gut microbiome changes significantly, which can impact digestion, immunity, and even the baby’s development.

 

How Prebiotics Work

 

  • Feed beneficial bacteria: Prebiotics help increase populations of healthy bacteria like Bifidobacteria and Lactobacilli.

  • Produce short-chain fatty acids: When fermented by gut bacteria, prebiotics generate compounds like acetate and butyrate, which support gut health and may influence the developing immune system in the fetus. Read about the mechanism of prebiotics for probiotics

  • Support immune function: A healthy gut microbiome can help regulate inflammation and immune responses, which is especially important during pregnancy.


Are Prebiotics Safe During Pregnancy?

 

If you’re wondering, can you take a prebiotic while pregnant or are prebiotics safe during pregnancy, the answer from current research is reassuring. Multiple studies and systematic reviews have found that prebiotic supplements are safe for use during pregnancy and lactation. Adverse effects are rare and usually mild, such as changes in stool consistency or mild gastrointestinal discomfort. See more on prebiotic safety and benefits

 

  • No increased risk of preterm birth: Reviews have found no evidence that taking prebiotics or probiotics during pregnancy increases or decreases the risk of preterm birth or other adverse outcomes for mother or baby.

  • Minimal side effects: Most reported side effects are mild and related to digestion, such as bloating or changes in bowel movements. See common side effects

  • No serious health concerns: There have been no reports of serious health risks for mother or infant associated with prebiotic supplementation during pregnancy or breastfeeding.


Prebiotics and Pregnancy: Potential Benefits

 

While the primary focus is always safety, many women are interested in the potential benefits of prebiotics pregnancy supplements.

 

Gut Health and Digestion

 

Pregnancy often brings digestive changes, including constipation and bloating. Prebiotics can help support regular bowel movements and a balanced gut microbiome, which may ease some digestive discomforts. Read about prebiotics for constipation

 

Immune System Support

 

The gut is closely linked to the immune system. By promoting a healthy gut microbiota, prebiotics may help support immune function in both mother and baby. Some studies suggest that prebiotics can help create a more tolerant immune environment for the developing fetus. See how prebiotics boost immunity

 

Fetal Development

 

Emerging research in animal models suggests that prebiotic supplementation during pregnancy can increase beneficial metabolites in the amniotic fluid, which may support fetal development. While more human studies are needed, these findings are promising. Learn more about prebiotics and fetal health


Taking a Probiotic While Nursing: Is It Safe?

 

Many new mothers ask, is it ok to take probiotics while nursing or is it ok to take probiotics while breastfeeding? The available evidence says yes—probiotic and prebiotic supplements are considered safe during breastfeeding. See Mayo Clinic’s advice

 

  • No harmful effects on infants: Studies have not found any increased risk of adverse outcomes for babies when mothers take probiotics or prebiotics while breastfeeding.

  • Possible benefits for baby: Some research suggests that taking a probiotic while nursing may help reduce the risk of eczema and allergies in infants, especially those with a family history of these conditions.

  • Supports maternal health: Probiotics and prebiotics may help mothers maintain healthy digestion and immune function during the postpartum period.


Human Milk Oligosaccharides (HMOs) and Effera™ Human Lactoferrin: The Next Generation of Prebiotics

 

At kēpos, we focus on human milk-equivalent ingredients—specifically, human milk oligosaccharides (HMOs) and Effera™ human lactoferrin. These bioactives are naturally found in breast milk and are now available in supplement form for adults. Discover how HMO prebiotics support digestive wellness

 

Why HMOs and Effera™ Human Lactoferrin?

 

  • HMOs: These are specialized prebiotics found in human milk. They selectively feed beneficial gut bacteria, especially Bifidobacteria, and act as decoys to block harmful pathogens.

  • Effera™ Human Lactoferrin: This is a bio-identical version of the lactoferrin protein found in human milk. It supports iron absorption, gut health, immune function, and has higher bioavailability and lower allergenicity compared to bovine lactoferrin.

  • Backed by research: Recent studies show that Effera™ human lactoferrin and HMOs can help reduce bloating, improve immune health, and support normal bowel function. See the latest on Effera™ human lactoferrin and HMOs research

 

How Are These Different From Other Prebiotics?

 

Most prebiotic supplements use plant fibers like inulin or fructooligosaccharides. While these are effective, HMOs and Effera™ human lactoferrin are unique because they are bio-identical to compounds in human milk, offering benefits that standard prebiotics cannot match. Learn more about prebiotic supplement benefits


What Does the Research Say About Prebiotics and Pregnancy?

 

Several reviews and studies have addressed the safety and effects of prebiotics during pregnancy and breastfeeding:

 

  • Safety confirmed: Systematic reviews confirm that prebiotics are safe for use during pregnancy and lactation, with no serious adverse effects reported. See Healthline’s review

  • Potential benefits: Animal studies suggest prebiotics may improve weight gain, immune system development, and metabolic health in offspring. Read the scientific review

  • Human studies needed: While animal data is promising, more robust human studies are needed to confirm the full range of benefits.


Should You Take a Prebiotic While Pregnant or Breastfeeding?

 

If you are considering prebiotic supplements during pregnancy or while breastfeeding, here are a few points to keep in mind:

 

  • Consult your healthcare provider: Always check with your doctor or midwife before starting any new supplement, especially during pregnancy and breastfeeding.

  • Choose high-quality products: Look for supplements with clear labeling, third-party testing, and clinical research backing their claims.

  • Consider human milk-equivalent prebiotics: HMOs and Effera™ human lactoferrin offer unique benefits and are designed to mimic the natural compounds found in breast milk.


Other Common Questions About Prebiotics, Probiotics, and Pregnancy

 

Can prebiotics help with pregnancy constipation?

 

Prebiotics can support regular bowel movements by feeding beneficial gut bacteria, which may help ease constipation—a common issue during pregnancy. See more about prebiotics for constipation

 

Are there any prebiotics to avoid during pregnancy?

 

Most commonly used prebiotics, such as inulin, FOS, and HMOs, are considered safe. However, always consult your healthcare provider, especially if you have a history of allergies or gastrointestinal disorders.

 

Do prebiotics affect gestational diabetes?

 

Some studies suggest that prebiotics and probiotics may help support healthy blood sugar levels, but results are mixed and more research is needed. Read the review on prebiotics and metabolic health

 

Can prebiotics impact the baby’s microbiome?

 

Yes, maternal intake of prebiotics can influence the composition of the baby’s gut microbiome, potentially supporting immune and metabolic health.

 

How do HMOs and Effera™ human lactoferrin compare to plant-based prebiotics?

 

HMOs and Effera™ human lactoferrin are bio-identical to compounds found in human breast milk, offering targeted benefits for gut and immune health that plant-based prebiotics cannot provide. Learn about HMO prebiotics


FAQs

 

Is it okay to take prebiotics while breastfeeding?

Yes, prebiotics are considered safe to use during breastfeeding, with no serious side effects reported for mothers or infants.


Is it safe to take prebiotics during pregnancy?

Current research shows prebiotics are safe during pregnancy, with only mild, temporary digestive effects in rare cases.


What supplements should I take while pregnant and breastfeeding?

Most healthcare providers recommend prenatal vitamins, iron, DHA, and sometimes probiotics or prebiotics. Always consult your doctor for a personalized plan.


Are probiotics safe for use during pregnancy and lactation?

Yes, studies confirm that probiotics are safe during pregnancy and breastfeeding, with minimal risk of side effects.


What are the main side effects of prebiotics in pregnancy?

  • Mild bloating

  • Changes in stool consistency